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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "lemur" in publications use:'
type: software
license: MIT
title: 'lemur: Latent Embedding Multivariate Regression'
version: 1.11.1
doi: 10.1038/s41588-024-01996-0
identifiers:
- type: doi
  value: 10.32614/CRAN.package.lemur
abstract: Fit a latent embedding multivariate regression (LEMUR) model to multi-condition
  single-cell data. The model provides a parametric description of single-cell data
  measured with treatment vs. control or more complex experimental designs. The parametric
  model is used to (1) align conditions, (2) predict log fold changes between conditions
  for all cells, and (3) identify cell neighborhoods with consistent log fold changes.
  For those neighborhoods, a pseudobulked differential expression test is conducted
  to assess which genes are significantly changed.
authors:
- family-names: Ahlmann-Eltze
  given-names: Constantin
  email: artjom31415@googlemail.com
  orcid: https://orcid.org/0000-0002-3762-068X
preferred-citation:
  type: article
  title: Analysis of multi-condition single-cell data with latent embedding multivariate
    regression
  authors:
  - family-names: Ahlmann-Eltze
    given-names: Constantin
    email: artjom31415@googlemail.com
    orcid: https://orcid.org/0000-0002-3762-068X
  - family-names: Huber
    given-names: Wolfgang
  journal: Nature Genetics
  year: '2025'
  doi: 10.1038/s41588-024-01996-0
repository: https://huber-group-embl.r-universe.dev
repository-code: https://github.com/const-ae/lemur
commit: 376f2f91309a5b15c19d6eb5e37ac6d99a2d3b88
url: https://github.com/const-ae/lemur
date-released: '2026-05-19'
contact:
- family-names: Ahlmann-Eltze
  given-names: Constantin
  email: artjom31415@googlemail.com
  orcid: https://orcid.org/0000-0002-3762-068X